Scalp Cooling Registry featured in the Clinical Services Journal
The May edition of the Clinical Services Journal (CSJ), a popular publication amongst medical professionals and a key source for updates in the medical field, features an article all about the Scalp Cooling Registry.
The Scalp Cooling Registry is the largest real-world, multicentre study focused on identifying the determinants of scalp cooling efficacy. Spanning over thirteen years (2006-19), the extensive registry includes data from 7,424 patients who underwent scalp cooling across 68 hospitals in The Netherlands. By examining patient outcomes across 24 different chemotherapy regimens, the study provides valuable insights into the determinants that affect efficacy of scalp cooling to mitigate chemotherapy-induced alopecia (CIA).
The Scalp Cooling Registry found the following results on overall efficacy.
The Scalp Cooling Registry was published in The Oncologist in 2024 and was authored by Toni S Brook, Tanja Seetsen, Marcus W Dercksen, Annemarie van Riel, Veerle A Derleyn, Johan van den Bosch, Johannes W R Nortier, Andrew Collett, Nikolas T Georgopoulos, Jarek Bryk, Wim P M Breed and Corina J G Van Den Hurk.
To date, it is the best snapshot we have of scalp cooling in the real world and a significant number of patients from this study used the Paxman Scalp Cooling System.
The article in the CSJ, written by Toni Brook, a co-author of the study, and Daniel Milner, Paxman’s Content Marketing Lead, shines a spotlight on the study findings and its implications for clinical practice.
Whilst the registry ruled out lifestyle tendencies, age, gender and hair type as influencing factors on scalp cooling success, it provided substantial data on average efficacy rates for scalp cooling. Analysing results across 24 chemotherapy regimens, drug type and dosage was the only ascertainable influential factor on what is classed as scalp cooling success – either a patient-reported outcome where a head covering was not required or clinician-assessed WHO alopecia score of 0 or 1 (equating to less than 50% hair loss). The study design, its assessment criteria, results, and implications for clinical practice are all summarised within the journal article, including the next steps for team behind the registry.
“The Scalp Cooling Registry is such a valuable set of data. We’ve never had data on such a large scale before that looks at mechanised scalp cooling in the real world. It’s an honour to have written this article alongside Toni and played a part in spreading the word about the great work she and her team have achieved. From the data, Paxman have been able to create an outcomes calculator based on chemotherapy regimen and offer more accurate hair retention estimates to the patients and clinicians we interact with.
“Hopefully, this encourages more clinicians to begin offering scalp cooling, giving patients a degree of control. If this can be done in the Netherlands, imagine a registry with an international scope, where we can eliminate any national disparities, increase cohort diversity, and assess differences in healthcare systems.”
– Daniel Milner, co-author of the article in the CSJ.
The article highlights Paxman’s commitment to collaborate with institutions and key clinical partners in disseminating the important work achieved. In this example, both Paxman and the authors of the registry are working towards the shared goals of understanding more deeply the determinants of scalp cooling, increasing awareness of its efficacy and enabling its plans for future registries on an international scale. We are therefore deeply grateful for our connections with these key figures in scalp cooling research and to the Clinical Services Journal for sharing our article with their audience.
To find out more about the Scalp Cooling Registry, including access to the manuscript, whitepaper and overview, visit scalpcoolingstudies.com/scalpcoolingregistry
