THE PAXMAN NEUROPATHY SYSTEM
The Paxman Neuropathy System
A breakthrough innovation for the chemotherapy side effect management space, the Paxman Neuropathy System helps reduce the risk of peripheral neuropathy progression while supporting patients to remain on their prescribed treatment.
The Paxman Neuropathy System consists of four major components designed to effectively reduce and maintain the temperatures for optimal results.
The System
The mobile, compact refrigeration unit responsible for maintaining cool temperatures of the hands and feet.
The Coolant
Uniquely engineered to continually extract heat from both hands and feet via the coolant lines.
The Gloves & Boots
Worn by the patient to ensure skin contact with the connected cooling layer.
The Compression Modules
Provide gentle cyclic pressure to the Gloves & Boots, increasing skin contact while ensuring comfort and tolerability.
Managing chemotherapy-induced neuropathy
Management of nerve damage during chemotherapy has been a major, unmet clinical need – until now. The Paxman Neuropathy System:
Offers the only CIPN management method to combine cooling with compression
Delivers cryocompression to both hands and feet simultaneously
Achieves safe, consistent, and tolerable temperatures
Fits seamlessly into oncology workflows
Is supported by clinical evidence and research
Can be used in conjunction with the Paxman Scalp Cooling System
With a 95% relative reduction of risk in incidence of ≥Grade 2 CIPN*, the Paxman Neuropathy System helps you continue the patient’s chemotherapy treatment cycle without dose modification.**
*NCI CTCAE, versus historical untreated control data.
**Clinical evaluation data available on request.
A cryocompression device for busy oncology clinics
Provides targeted cooling and compression of the hands and feet, supporting delivery of a biologically informed cooling range of 20-24°C (68-75°F) at the time of infusion.
Continual cooling capabilities ensure immediate treatment readiness when the patient is connected, following a short 30-minute refrigeration period at the start of each day.
User-friendly controls and clear on-screen guidance to reduce nursing burden.
Automated cryocompression programmes make treatment easy to administer.
Compact, miniaturised, and transportable design allows two systems to be used at once on the accompanying trolley – a Paxman Scalp Cooling System or another Paxman Neuropathy device. Ideal for infusion sites where space is at a premium.
Designed to achieve low temperatures
A uniquely engineered coolant with ultra-efficient heat transfer properties.
Continuous flow of coolant extracts heat from the hands and feet, maintaining target temperatures for the best results.
Cooling for efficacy. Compression for comfort
The Paxman Gloves and Boots are where cooling meets compression for reliable performance.
Coolant is delivered through innovatively designed cooling bladders, with channels that follow the anatomy and natural contours of the hands and feet, enhancing heat extraction and ensuring a consistent treatment experience.
Cyclic pressure delivered via an air compression pouch produces a therapeutic massaging sensation supporting tolerable delivery of lower temperatures.
Flow indicators offer fast, effortless monitoring of coolant.
Designed for easy fitting and removal, with a stretchy material, various sizes, and Velcro loop adjustments to enhance comfort.
Compelling evidence for a significant unmet need
Discover the clinical data and patient outcomes that demonstrate how the Paxman Neuropathy System revolutionises CIPN management, including efficacy, safety, and tolerability.
Remove difficult decisions around chemotherapy-induced peripheral neuropathy
The most recent guidelines from ASCO indicate that, in times when patients exhibit significant neuropathy, physicians must evaluate whether treatment delay, dose modification, substitution or cessation of chemotherapy are required.1
This presents the difficult choice: choose a less effective cancer treatment or risk allowing CIPN to progress. Through controlled and reproducible cooling and compression, Paxman is transforming CIPN from an unavoidable consequence of neurotoxic chemotherapy into a manageable side effect.
A more sustainable choice
Materials within the Paxman Gloves and Boots are highly recyclable, reducing the environmental footprint of the treatment.
First-class training and support
You and your patients are never left out in the cold. From start to finish, benefit from extensive training and comprehensive patient resources, allowing you to deliver each chemotherapy regimen with confidence.
How cryocompression could help reduce CIPN
Biological rationale and early clinical data suggest that cryocompression could become an important part of chemotherapy side-effect management, helping services protect patients from both cancer and the long-term consequences of its treatment.
Used in cancer treatment centres across the world
References
- Charles L. Loprinzi et al. Prevention and Management of Chemotherapy-Induced Peripheral Neuropathy in Survivors of Adult Cancers: ASCO Guideline Update. J Clin Oncol 38, 3325-3348(2020). DOI:10.1200/JCO.20.01399
